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The creatures start to adapt and evolve at an exponential rate, becoming increasingly aggressive and powerful. Anika and Jack realize that they have created something that is beyond their control and potentially very dangerous.

In a shocking twist, Anika decides to sacrifice herself to save Jack, allowing him to escape from the laboratory. As Jack flees, Graver and Frank are seen escaping into the wilderness, leaving the audience with a haunting and unsettling conclusion.

2009

Their first successful experiment results in the creation of a creature that is a hybrid of a human and a rat. The creature, which they call "Frank" (named after the Frankenstein monster), seems to possess incredible healing abilities.

Anika and Jack are initially hesitant, but the prospect of making a groundbreaking discovery and getting ahead in their careers convinces them to proceed. They start experimenting with splicing animal genes into human cells, and vice versa.

Encouraged by their success, Anika and Jack decide to create another creature, this time splicing human DNA with that of a more complex animal, a wolf. The new creature, which they call "Graver", grows at an alarming rate and displays incredible strength and agility.

Overall, "Splice" is a thought-provoking and unsettling film that raises important questions about the ethics of scientific experimentation and the consequences of playing with nature.